Seminar & Colloquium
[세미나: 8월 28일(월), 오후 4시] prof. Seokho Kim, Department of Medical Biotechnology, Dong-A university
Title
NK cells: from Bench to Clinic
Speaker
prof. Seokho Kim, Department of Medical Biotechnology, Dong-A university
Education
- 2005 ~ 2009. 5. Ph.D., Graduate school of Molecular medicine, Chonnam National University
- 2002 ~ 2004. 5. M.S.,Graduate school pf Animal Science, Chonnam National University
- 1995 ~ 2001. 8. B.S., Dept. of Animal science, Chonnam National University
Experience
- 2019. 9. ~ Assistant Professor of Dong-A university
- 2011 ~ 2019. 8. Senior Researcher, Aging Intervention Research Center, KRIBB
- 2015 ~ 2019. 8. Professor of UST(University of Science & Technology)
- 2011 ~ 2011 Visiting Fellow., NIH-NCI(National Cancer Center)
- 2009 ~ 2011 Post-Doc., Dept. of Orthopedic surgery, Washington University, USA
| Date | Monday, August 28th, 2023
| Time | 16:00 ~
| Venue | 신소재공동연구소 1층 세미나실
[Abstract]
Recently, Immunotherapy is an alternative medicine to chemical based drugs for treatment of cancer. Among the immunotherapy, natural killer cell is a useful treatment material that, unlike T cells, does not require immune education and does not have side effects such as GVHD. Many of groups have developed methods to improve expansion and cytotoxicity of natural killer cells for treatment of cancers. However, natural killer cells have a number of limitations in manufacturing off-the-shelf as pharmaceuticals. In particular, large-scale GMP facilities, many of experts for handling cells, and cold chain for logistics are obstacles to overcome. To do this, we try to develop a new method for mass production of natural killer cells through an automated process through a portable small GMP facility. Based on feeder cells and cytokines combination, we have established a technology to amplify natural killer cells more than 2000 times through various cytokine combinations. Furthermore, we confirmed potential as medical drug for treatment of cancers through tumor bearing mouse. Taken together, we have established a one-stop process for mass production of natural killer cells automatically. Furthermore, we intend to conduct clinical trial by using these cells this year.
| Host | 강승균 교수(02-880-5756)