Seminar & Colloquium
[세미나: 6월 20일(화), 오후 4시] Prof. Jinsang Kim, University of Michigan
Title
Rational Molecular Design of Organic Functional Materials for Bioensors and Optoelectronics
Speaker
University of Michigan, Prof. Jinsang Kim
EDUCATION
- 2008.09 ~ 2013.08 Ph.D., Department of electrical engineering, KAIST, Korea
- 2006.09 ~ 2008.08 M.S., Department of electrical engineering, KAIST, Korea
- 2001.03 ~ 2006.08 B.S., Department of electrical engineering, Kyungpook National University, Korea
Biography
Jinsang Kim is a Professor and Director of Macromolecular Science and Engineering, and a Professor of Materials Science and Engineering having a joint appointment in the Chemical Engineering, Biomedical Engineering, and Chemistry at the University of Michigan, Ann Arbor. He holds a M.S (1993) and a B.S. (1991) from Seoul National University, Korea, both in Fiber and Polymer Science. He earned his Ph.D. in 2001 in Materials Science and Engineering from MIT (Advisor Prof. Tim Swager), where he studied the design, synthesis, and assembly of conjugated sensory polymers and energy transport properties in controlled structures. He is also an expert in genetically engineered protein research. His postdoctoral work in this area at Caltech (Advisor Prof. David Tirrell) involved the expression of artificial genes to determine the extent to which artificial genetic information can be used to encode supramolecular assembly in macromolecular systems.
He has won several prestigious awards including Monroe-Brown Foundation Research Excellent Award, NSF CAREER Award, Holt Award for excellent teaching, IUPAC Prize for Young Chemist, and the ACS ICI Award. He was also named one of the emerging investigators by the Journal of Materials Chemistry in 2007. His current research interests at the UM are plastic electronics, self-signal amplifying molecular biosensors, highly emissive organic emitters, and high performance polymers. His research has been sponsored by NSF BES, NSF ECS, NSF DMR, AFOSR, ARO, DoE, NIH, ACS, KIMM, KRF, QIA, Qatar NRF, Ford, Samsung, LG Chem, and Center for Chemical Genomics.
| Date | Tuesday , June, 20th, 2023
| Time | 16:00 ~
| Venue | 33동 228호
[Abstract]
Conjugated polymers (CPs) and organic molecules have become emerging materials for many modern technologies due to their readily tunable properties by variation of chemical structure and easy fabrication. Particularly the sensor application of CPs has gained much interest recently because CP-based sensors can provide large signal amplification. Our self-signaling optical sensors are designed to achieve high sensitivity by means of the external stress-responsive optical property of conjugated polymers. Receptors are rationally designed to provide specificity toward a target analyte to realize high selectivity. We have developed conjugated polymer-based optical sensory systems to detect various target molecules such as DNA, proteins, metal ions, influenza virus, antibiotics, prostate specific antigen, nerve agents, and melanin. The concept, design principles, and applications of CPs for self-signaling sensors and sensor arrays will be discussed.
Novel sensory systems based on emissive super-cooled liquids and metal-free purely organic phosphors will also be presented. In our recent development of highly emissive and metal-free purely organic phosphorescence materials for the last decade, directed intermolecular heavy atom effects were rationally implemented in aromatic carbonyl molecules to promote spin-orbit coupling and suppress vibrational dissipation. Color tuning by electron density modulation was successfully implemented in the metal-free purely organic phosphors (POPs). Due to rather slow electron spin flipping during phosphorescence emission of POPs, molecular engineering to prevent collisional energy dissipation turned out to be critical to achieve bright phosphorescence emission in ambient conditions. On the other hand, the same slow phosphorescence feature renders highly sensitive oxygen quenching via energy transfer from POP’s triplet state to surrounding oxygen molecules in the ground state. This unique phenomenon has been utilized in a newly devised lipid-polymer hybrid POP turn-on nanoprobe for chorioretinal hypoxia detection in vivo using rabbit retinal vein occlusion and choroidal vascular occlusion models.
| Host | 권민상 교수 (02-880-8326)